Adipose triglyceride lipase in immune response, inflammation, and atherosclerosis
نویسندگان
چکیده
منابع مشابه
Adipose triglyceride lipase in immune response, inflammation, and atherosclerosis.
Consistent with its central importance in lipid and energy homeostasis, lipolysis occurs in essentially all tissues and cell types, including macrophages. The hydrolytic cleavage of triacylglycerol by adipose triglyceride lipase (ATGL) generates non-esterified fatty acids, which are subsequently used as essential precursors for lipid and membrane synthesis, mediators in cell signaling processes...
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Lipolysis is the catabolic pathway by which triglycerides are hydrolyzed into fatty acids. Adipose triglyceride lipase (ATGL) and hormone-sensitive lipase (HSL) have the capacity to hydrolyze in vitro the first ester bond of triglycerides, but their respective contributions to whole cell lipolysis in human adipocytes is unclear. Here, we have investigated the roles of HSL, ATGL, and its coactiv...
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1 myocytes, impairs acute exercise performance in mice 2 3 4 5 6 John J. Dubé, Mitch T. Sitnick, Gabriele Schoiswohl, Rachel C. Wills, Mahesh K. Basantani, 7 Lingzhi Cai, Thomas Pulinilkunnil, and Erin E. Kershaw 8 9 10 11 Affiliation 12 Division of Endocrinology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA 13 2 Department of Biochemistry and Molecular Biology, Dalhousie Me...
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ژورنال
عنوان ژورنال: Biological Chemistry
سال: 2012
ISSN: 1437-4315,1431-6730
DOI: 10.1515/hsz-2012-0192